Event Probabilities

Description

Class for the definition of event probabilities.

Details

EventProbabilities is a class for the definition of event probabilities.

Fields

time

The time values. Is a numeric vector.

accrualTime

The assumed accrual time intervals for the study. Is a numeric vector.

accrualIntensity

The absolute accrual intensities. Is a numeric vector of length kMax.

kappa

The shape of the Weibull distribution if kappa!=1. Is a numeric vector of length 1.

piecewiseSurvivalTime

The time intervals for the piecewise definition of the exponential survival time cumulative distribution function. Is a numeric vector.

lambda1

The assumed hazard rate in the treatment group. Is a numeric vector of length kMax.

lambda2

The assumed hazard rate in the reference group. Is a numeric vector of length 1.

allocationRatioPlanned

The planned allocation ratio (n1 / n2) for the groups. For multi-arm designs, it is the allocation ratio relating the active arm(s) to the control. Is a positive numeric vector of length 1.

hazardRatio

The hazard ratios under consideration. Is a numeric vector of length kMax.

dropoutRate1

The assumed drop-out rate in the treatment group. Is a numeric vector of length 1 containing a value between 0 and 1.

dropoutRate2

The assumed drop-out rate in the control group. Is a numeric vector of length 1 containing a value between 0 and 1.

dropoutTime

The assumed time for drop-out rates in the control and treatment group. Is a numeric vector of length 1.

maxNumberOfSubjects

The maximum number of subjects for power calculations. Is a numeric vector.

overallEventProbabilities

Deprecated field which will be removed in one of the next releases. Use cumulativeEventProbabilities instead.

cumulativeEventProbabilities

The cumulative event probabilities in survival designs. Is a numeric vector.

eventProbabilities1

The event probabilities in treatment group 1. Is a numeric vector.

eventProbabilities2

The event probabilities in treatment group 2. Is a numeric vector.